In the sermon "Look Up, Look Forward", Simon Chase focuses on the Christian life according to the teachings of the Apostle Paul, especially from the book of Colossians. He emphasizes the importance of living a life rooted in Christ, highlighting the transformation that occurs when one becomes a Christian. Simon encourages the congregation to maintain a heavenly perspective, focusing on Christ's teachings and the promise of eternal life, instead of getting entangled in worldly concerns and human traditions. The sermon also reminds Christians of their identity in Christ and the empowerment they receive through faith.