Pastor Jamie's sermon focuses on the sanctity of life, exploring how a secular worldview leads to devaluing life, while the gospel affirms its inherent worth. He contrasts the world's views on the origin, dignity, and beginning of life with the biblical truth that life is fearfully and wonderfully made by God. Through Scripture, such as Psalm 139 and Genesis 1, he emphasizes that life has divine purpose and value because God created it, not because humans assign it worth. He calls believers to courageously uphold life, rooted in the gospel, while showing love and compassion in addressing sensitive issues like abortion.